Research
Eagle 2
A new antibiotic for the treatment of uncomplicated Urinary Tract Infection ( UTI) in female adults and adolescents sponsored by GSK .
Uncomplicated Urinary Tract Infections are the most common outpatient infection with over half of all women developing a UTI during their lifetime and more than a quarter of women suffering recurrent UTIs.
OPTIMISE 2
Optimising Treatment for Mild Hypertension in Older People at Risk of Adverse Events
The OPTIMISE 2 trial will establish whether deprescribing common drugs that lower blood pressure is safe or effective in older people in the longer term (a year or more).
Moderna 1273
Omicron BA.1 – containing mRNA 1273 boosters compared with the original Covid-19 vaccine in the UK : a randomised, observer blind, active controlled trial
Background/Overview
The Omicron BA.1 bivalent booster is used globally . Previous open label studies of the Omicron BA.1 booster showed superior antibody response compared with the original mRNA 1273 booster . This study aims to compare the safety and immune response from the Omicron Boosters ( monovalent and bivalent) with the original MRNA-1273 vaccine in a large randomised control trial
Novartis study CKJX839D12302
A randomized, double-blind, placebo-controlled multicenter study to evaluate the effect of inclisiran on preventing major adverse cardiovascular events in high-risk primary prevention patients (VICTORION-1 PREVENT)
This study started enrolling in Autumn 2023 and has now enrolled 14,000 participants in over 45 countries
Nova 301 Trial
Join the Nova 301 Trial to find out if we can protect people 60 years of age or older against norovirus stomach bug symptoms
Enrolling Adults 60+: Help to see if we can protect people against symptoms caused by the norovirus stomach bug with an investigational mRNA vaccine
Fluent 1010
A clinical trial for an investigational mRNA seasonal flu vaccine
Seasonal flu can cause serious illness, especially for older people
In winter, seasonal flu can cause thousands of people in the UK to receive hospital treatment every day
The Fluent Trial is looking to recruit more than 56,000 people across Europe, North America and Asia to help research into an investigational mRNA jab against seasonal flu
Study of a vaccine for the prevention of Respiratory Syncytial Virus
GSK RSV - 012
Study of a vaccine for the prevention of Respiratory Syncytial Virus (RSV) infection and revaccination 222090 (RSV OA=ADJ-012)
Efficacy of AReSVi Vaccine in the Prevention of Respiratory Synctital Virus Types A and B
RSV is a common contagious virus affecting the lungs and breathing passages. It is one of the major remaining infectious diseases for which there is currently no vaccine or specific treatment.
LightHouse
The purpose of this study was to collect blood samples and medical information to help develop and evaluate a blood test that can screen for many cancers, including but not limited to lung, colorectal, ovarian, pancreatic, liver, bladder, stomach and oesophageal cancer from a single blood sample collection.
